Resistance profiles of urinary tract infections in general practice - an observational study
نویسندگان
چکیده
BACKGROUND Guideline recommendations on therapy in urinary tract infections are based on antibiotic resistance rates. Due to a lack of surveillance data, little is known about resistance rates in uncomplicated urinary tract infection (UTI) in general practice in Germany. In a prospective observational study, urine cultures of all women presenting with urinary tract infections in general practice were analysed. Resistance rates against antibiotics recommended in German guidelines on UTI are presented. METHODS In a prospective, multi-center observational study general practitioner included all female patients ≥ 18 years with clinically suspected urinary tract infection. Only patients receiving an antibiotic therapy within the last two weeks were excluded. RESULTS 40 practices recruited 191 female patients (mean age 52 years; range 18-96) with urinary tract infections. Main causative agent was Escherichia coli (79%) followed by Enterococcus faecalis (14%) and Klebsiella pneumoniae (7.3%).Susceptibility of E.coli as the main causative agent was highest against fosfomycin and nitrofurantoin, with low resistance rates of 4,5%; 2,2%. In 17,5%, E.coli was resistant to trimethoprim and in 8,5% to ciprofloxacin. CONCLUSIONS Resistance rates of uropathogens from unselected patients in general practice differ from routinely collected laboratory data. These results can have an impact on antibiotic prescribing and treatment recommendations.
منابع مشابه
Author's response to reviews Title: Resistance profiles of urinary tract infections in general practice - an observational study Authors:
متن کامل
بررسی عوامل موثر بر عفونت ادراری در بارداری
Introduction: Women are very susceptible to urinary tract infections and pregnancy raises the risk of urinary tract infection. In general, little information on the risk factors of urinary tract infection in pregnancy is underway. Urinary tract infection in pregnancy is an important risk factor for pregnancy dire consequences. The purpose of this study is to find risk factors associated with ur...
متن کاملInvestigation of prevalence and antibiotic resistance pattern of bacteria isolated from urinary tract infections in women referred to Ghaem hospital in Mashhad
Background: Urinary tract infection (UTI) is one of the most commonly problematic bacterial infections, especially among women. Increasing drug resistance requires the determination of an antibiotic resistance pattern for proper treatment. Therefore, this study aimed to investigate the prevalence and antibiotic resistance against bacterial agents isolated from urinary tract infections in women ...
متن کاملPrevalence and Microbiological Profile of Catheter Associated Urinary Tract Infections: A Case Study in Secondary Care Hospital
Background and Objectives: Healthcare-associated infections is a major health care concern posing potentially serious negative impact on patient safety and outcome. In this paper, we report this microbiological profile and the prevalence of Catheter Associated Urinary Tract Infections (CAUTIs). Methods: This was a prospective observational study for...
متن کاملAntibiotic resistance pattern and serotyping of Escherichia coli producing siderophore in people with urinary tract infection
Urinary tract infection is one of the most common bacterial infections of human. The most common agent of urinary tract infection is Escherichia coli . This study aims to determine the prevalence of uropathogenic E. coli urinary infection in human with different antimicrobial resistance, and quantitive and qualitative study of siderophore production and their association with the ability to cau...
متن کامل